Picamilon Tablets

Picamilon - A “feel good” nootropic for anxiety and stress relief. ✝

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Sachet of 6 tabs x 100mg Bottle of 60 tabs x 100mg



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What is Picamilon?

Picamilon is a nootropic compound that was developed by combining GABA (the key inhibitory neurotransmitter) and niacin (Vitamin B3). By combining these two nutrients into one formula, scientists in the Soviet Union were able to get a range of cognitive enhancing and neuroprotective effects. This GABA-containing vitamin agent reaches the brain easier than two compounds taken separately. It has been used in humans for over 30 years.

Interestingly, Picamilon is a hybrid nootropic as it has tranquilising and mild stimulant properties combined into one compound. Its tranquilising effects without a sedative component prevent the negative effects of emotional stress, whilst stimulatory action provides a boost in mental energy. It also increases the blood flow and circulation in the brain. Some evidence suggests that it may be so effective that it even rehabilitates overstrain working capacity.

Over-excited neural activity in the brain is regulated by GABA, which prevents stress reactions and leads to a calm state. Hence, Picamilon is often used by people who suffer from mood disturbance (irritability), emotional instability and high levels of anxiety. Other positive nootropic effects include an increase in mental well-being, motivation and drive.  

Overall, Picamilon is more effective as a mood enhancer and regulator than a cognitive enhancer.

Key benefits:

  • Reduces emotional stress
  • Anti-anxiety effect
  • Stress reliever
  • Mood stabilizer
  • Improves working capacity
  • Increased mental alertness

Mechanisms of action:

Picamilon works by rapidly crossing the blood-brain barrier where it is split into its two main components - GABA and niacin. GABA is then free to bind to receptors and produce an anxiolytic effect. Niacin decreases cerebral blood vessels tone and causes vasodilation which increases blood flow and circulation in the brain. A combined action of these two nutrients improves the functional state of the brain. Picamilon usually starts to work within an hour and its effects last between 4-6 hours.

Recommended dosage:

The recommended dosage is between 50 -100 mg, taken three times per day. Lower doses (i.e., 50 mg) are used for tranquilizing and mood stabilizing effects, whereas higher doses (i.e. 100 mg) provide a stimulatory effect for increased mental energy and endurance. After prolonged use (i.e., several weeks of daily usage) Picamilon’s effects become cumulative and more evident. The above dosages should be reduced when taken with other nootropics as Picamilon is believed to be synergistic.

Side effects:

Picamilon is generally considered safe with a very low toxicity and no allergenic or carcinogenic properties. However, Picamilon should not be taken with any sedative medications as it can potentially enhance their effects. Also, minimal side effects may include occasional headaches, nausea and dizziness.

Compound facts:

Serving size: 1 tablet

Servings per bottle: 60

Amount per serving: Picamilon 100 mg

Other ingredients: Magnesium Stearate; Silicon Dioxide

This product is free from: Artificial Flavours, Colours & Preservatives, Lactose, Yeast & Gluten

Suitable for: Vegetarians and Vegans


  • Dietary products should not be used as a substitute for a well-balanced and healthy diet.
  • Store in a cool dry place, out of reach of children.
  • Do not use if you are pregnant or breastfeeding.


✝ These statements have not been evaluated by the Food and Drug Administration (FDA) The above products are not intended to diagnose, treat, cure or prevent any disease. You should consult a physician before taking a new product or a nootropic. This product should not be taken by pregnant or nursing mothers, people suffering from cardiovascular disease or those under 18 years of age.

Any studies cited here are not conclusive and are limited to their closed environment nature; they might not determine ones experience with a nootropic, due to a large number of unaccounted variables falling outside the scope of such studies.

The reviews available here are the opinions of contributors who may or may have not used these products, and do not necessarily represent the views of ThoughtFoods. These reviews represent one’s opinion and should not be taken as fact or recommendation. ThoughtFoods makes no warranty to the accuracy of information provided by these reviews. Read legal disclaimer

Picamilon Tablets Reviews

ThoughtFoods Picamilon Tablets

4.5(based on 13 reviews)

By Ricardo G.
The customer has rated the product but has not posted a review, or the review is pending moderation

By Ahg V. on04 Aug. 2016
Good value for money and fast
Good value for money and fast
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By Julian Z. on29 June 2016
Extremely effective..
Actually too effective, for me: I would have preferred 5mg doses rather than 10mg. The small tablets don't split easily, becoming irregular lumps and crumbs.. Also, as mentioned in my other review, the ordering database 'cart' is flaky. As for Picamilon itself, I'd say it's a more practical/sensible/well-modulated version of Phenibut.
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By Vytautas S.
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By Imrad S. on22 Feb. 2016
Stress levels = controlled
Under and huge amount of stress lately, picamilon has helped keep those stress levels under control and deal-able. No side effects of note, also started to take steps in life to help reduce these high stress levels.
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