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Coluracetam is a relatively new compound in the racetam family. The structure and mechanisms of action of Coluracetam are reported to be different compared to other racetams (e.g. Piracetam and Aniracetam). Coluracetam is a choline-uptake enhancer as it regulates the rate-limiting process whereby choline is drawn into a neuron in order to be converted into the neurotransmitter acetylcholine. Therefore it facilitates the synthesis, release and availability of acetylcholine which is a very important neurotransmitter involved in a number of cognitive processes, such as memory formation, learning and focus. By increasing the speed of this process the activity of cholinergic neurons is improved.
Overall, Coluracetam is a potent nootropic for memory and learning capacity enhancement. As a secondary benefit, the symptoms of depression and anxiety may be reduced.
Precise mechanisms of action are still unknown but it appears that Coluracetam increases transportation of high-affinity choline transporters and enhances choline uptake in the hippocampus. In other words, Coluracetam makes the body and brain more efficient at up taking and using choline. Coluracetam has also been shown to facilitate AMPA potentiation. Coluracetam becomes active within 30 minutes after ingestion and stays the most effective for around 3 hours. Biological half-life of Coluracetam is around 3 hours. Therefore, precise timing of its administration is very important to ensure optimal effects.
The recommended daily dosage is between 120 - 200 mg taken in 3 equal administrations throughout the day. It is important to mention that, as with other racetams, there is a large individual variation with regards to sensitivity to this nootropic. Therefore, you should start with lower dosages and observe the benefits you get. Some users report that as low as 100 mg/day is very effective.
Coluracetam is thought to be a safe and non-toxic nootropic. There are no reported adverse side effects when used within the recommended dosage.
Serving size: 1 tablet
Servings per bottle: 60
Amount per serving: Coluracetam 30 mg
Other ingredients: Magnesium Stearate; Silicon Dioxide
This product is free from: Artificial Flavours, Colours & Preservatives, Lactose, Yeast & Gluten
Suitable for: Vegetarians and Vegans
✝ These statements have not been evaluated by the Food and Drug Administration (FDA) The above products are not intended to diagnose, treat, cure or prevent any disease. You should consult a physician before taking a new product or a nootropic. This product should not be taken by pregnant or nursing mothers, people suffering from cardiovascular disease or those under 18 years of age.
Any studies cited here are not conclusive and are limited to their closed environment nature; they might not determine ones experience with a nootropic, due to a large number of unaccounted variables falling outside the scope of such studies.
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