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Nefiracetam is a nootropic compound that belongs to the racetam family. As other racetams it was synthesised from Piracetam, but due to structural similarities Nefiracetam is often compared to Aniracetam.
Nefiracetam activates the cholinergic, GABAergic and monoamigernic systems. In addition, Nefiracetam helps open calcium channels in the activated neurons which subsequently amplifies the message sent by the neurotransmitters. Calcium influx is important for the long-term potentiation (LTP). LTP is the process by which signal transmission between the two simultaneously active neurons is strengthened. LTP is demonstrated in the hippocampus, an area of the brain that is especially important in the formation and retrieval of memory.
Users of Nefiracetam report a wider range of benefits in comparison to other racetams, such as Piracetam and Aniracetam. These include improved memory, learning capacity, and spatial learning. In addition, Nefiracetam is one of the best nootropics if you are looking to improve your attention span, focus and concentration. Nefiracetam may also have anti-depressant properties and ensure a healthy functioning of neurons in the brain.
Two main mechanisms of action have been proposed. Firstly, Nefiracetam appears to increase the release of acetylcholine and glutamate neurotransmitters. This results in an increased rate of signalling through cholinergic receptors. Secondly, it potentiates the NMDA receptors through protein kinase C. NMDA is associated with memory function and neuroplasticity. Nefiracetam can be detected within 30-60 minutes post-ingestion. Biological half-life of Nefiracetam is 3-5 hours.
The recommended daily dosage is between 150 and 400 mg taken in 3 even doses over the course of a day. A single dosage appears to have no acute effect on memory formation. Therefore, for maximum results it is recommended to take Nefiracetam over a longer period of time (at least 7 days). This will also result in a better neurons formation.Nefiracetam is a fat soluble nootropic that needs to be ingested with a fat containing meal. This will help it cross the blood-brain barrier quicker.
There seems to be no serious toxic effects in healthy individuals when taken at the recommended dosages. However, some occasionally reported mild side effects, such as irritability, headaches, stomach ailments and nausea, are comparable to those of other racetams. To prevent the headaches you can add a choline compound (e.g. Choline Bitartrate and Alpha GPC) to your stack. Unless used in excessively high doses you should not experience any other side effects.
Serving size: 1 capsule
Servings per bottle: 60
Amount per serving: Nefiracetam 400 mg
Other ingredients: Magnesium Stearate; Silicon Dioxide
This product is free from: Artificial Flavours, Colours & Preservatives, Lactose, Yeast & Gluten
Suitable for: Vegetarians and Vegans
✝These statements have not been evaluated by the Food and Drug Administration (FDA) The above products are not intended to diagnose, treat, cure or prevent any disease. You should consult a physician before taking a new product or a nootropic. This product should not be taken by pregnant or nursing mothers, people suffering from cardiovascular disease or those under 18 years of age.
Any studies cited here are not conclusive and are limited to their closed environment nature; they might not determine ones experience with a nootropic, due to a large number of unaccounted variables falling outside the scope of such studies.
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